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Andrews et al compared the muscle-relaxant effect of the two agents under propofol anesthesia in patients undergoing surgery.
Mazurek et al assessed the quality of muscle paralysis and intubation conditions with SCh 1. The two agents were shown to produce comparable intubation conditions in children The problem of slightly longer onset time of RCR compared to SCh was addressed by Nelson et al in a prospective randomized, double-blind comparison study in 42 patients undergoing elective surgery To compare the pharmacodynamics of two commonly recommended doses of RCR 0.
Authors indicated that patients who received RCR 0. RCR at a dose of 0. Optimal airway management requires utilization of a variety of pharmacologic adjuncts proved useful in obtaining a secure airway and minimizing risk to the patient. SCh has been shown to cause many adverse effects including fatal bradycardia, fasciculation and hyperkalemia.
A non-depolarizing muscle relaxant, RCR that is free of side effects and has comparable onset time may be viewed as a suitable alternative to SCh. Keywords muscle paralysis, neuromuscular blockade, rapid sequence induction, rapid sequence intubation, rocuronium, succinylcholine. Abstract Succinylcholine is the single ultra-short acting depolarizing neuromuscular blocking agent NMBA used in the rapid sequence intubation protocol with its rapid onset of effect, complete reliability, short duration of action.
Introduction Rapid sequence intubation RSI is developed to secure the airway of a critically ill or injured patient rapidly and safely. Clinical And Pharmacological Properties Of Each Agent Introduced in , SCh depolarizes the neuromuscular membrane and is structurally consisted of two acetylcholine molecules. Conclusion Optimal airway management requires utilization of a variety of pharmacologic adjuncts proved useful in obtaining a secure airway and minimizing risk to the patient.
Acad Emerg Med;7 In Rosen P, Barkin R. Concept and Clinical Practice. Louis , 4th ed. Manual of Emergency Airway Management. Tracheal intubation and mechanical ventilation. A Comprehensive Study Guide. Pharmacologic adjuncts to intubation. Comparison of intubating conditions after rocuronium and suxamethonium following "rapid-sequence induction" with thiopentone in elective cases.
Acta Anaesth Scand, Tracheal intubation with rocuronium using the "timing principle". Comparison of rocuronium, succinylcholine, and vecuronium for rapid-sequence induction of anesthesia in adult patients. Intensive care anesthesia and analgesia. Current critical care diagnosis and treatment. Bradycardia following intravenous administration of succinylcholine chloride to infants and children. The effect of rocuronium on intraocular pressure: Eur J Anaesthesiol ;18 Rocuronium versus succinylcholine-atracurium for tracheal intubation and maintenance relaxation during propofol anesthesia.
J Clin Anesth;12 6: Lim K, Smith AF Effect of rocuronium compared with succinylcholine on IOP. Br J Anaesth , 83 5: Onset of neuromuscular block at the masseter and adductor pollicis muscles following rocuronium or succinylcholine. Can J Anaesth , 46 Effect of rocuronium compared with succinylcholine on intraocular pressure during rapid sequence induction of anaesthesia.
Br J Anaesth, 82 5: Intraocular pressure changes during rapid sequence induction and intubation: J Clin Anesth, 11 2: Effects of an intubating dose of succinylcholine and rocuronium on the larynx and diaphragm: A large simple randomized trial of rocuronium versus succinylcholine in rapid-sequence induction of anaesthesia along with propofol. Acta Anaesthesiol Scand, 43 1: Read these tips and trade more profitably immediately Professional traders.. It is used to implement the backtesting of the trading strategy.
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